The Commission of the European Union (EU) has established a maximum residue limit (MRL) for hydrocortisone aceponate.
Hydrocortisone aceponate is a corticosteroid that is often used to reduce inflammation in skin and tissues and is sometimes found in veterinary medicinal and biocidal products. The Annex to EU Regulation (EC) No 470/2009 establishes MRLs for a number of pharmacologically-active substances found in medicinal products used with food-producing animals. However, hydrocortisone aceponate was not previously included on the list of substances and their MRL classification in foodstuffs of animal origin, as presented in the Regulation’s Annex.
The European Medicines Agency (EMA) recently recommended the establishment of an MRL for hydrocortisone aceponate in bovine tissues and milk, and restricting its use in animals to intramammary tissue only. Accordingly, the Commission has issued an Implementing Regulation, amending the Annex to establish an MRL for hydrocortisone aceponate of 10µg/kg in milk tissues.
The full text of the Commission’s Implementing Regulation on hydrocortisone aceponate is available here.